While ever wishing to have a major deficiency in normal parts of the body would be a bad thing, it might not be in some specific situations. When it comes to rare genetic traits, one might love to have a deficiency in their Proprotein Convertase Subtilisin/Kexin Type 9 gene. Otherwise known as the PCSK9 gene, some people are born with a much smaller amount of this gene than the rest of us.
[Image via MDGRPHCS/Shutterstock.com]Having this deficiency can be a blessing in disguise, as it allows a person to have a reduced risk of heart disease by up to as much as 90 percent! On top of this, they do not have to worry about their cholesterol numbers like others. However, this deficiency does come with some drawbacks. The deficiency allows one to have an increased number of cholesterol esters, but this will impact glucose-stimulated insulin secretion. That will cause hyperglycemia and even impaired glucose tolerance.