- Debut: Batman #181 (April 1966)
- Created By: Robert Kanigher & Sheldon Moldoff
Poison Ivy technically does not have bad aspirations. She wants mankind to take better care of Mother Earth, which seems like a fair ask. However, mankind is not exactly proving today that they are willing to do this. Originally just an Earth-loving scientist named Dr. Pamela Isley, she is always upset at how mankind treats Earth but clearly cannot do much about it herself. The botanist is working at a local university when she is seduced by her professor, Dr. Jason Woodrue. The normally shy and reserved Isley is injected with poisons and toxins by Woodrue as an experiment. These toxins and poisons nearly kill her twice, but Isley manages to live. However, she is now transformed but insane from the experiments.
This is something that Woodrue found out the hard way. Her shy nature is gone in favor of an open, seductive woman who uses pheromones or kisses to get humans to do as she commands. Those kisses if held long enough can end lives too due to their toxicity. Pamela also finds she can control plants and other Earth-based materials, making her a massive meta-human threat. Taking on the Poison Ivy moniker, she becomes an eco-terrorist with the goal of forcing normal humans to take care of the Earth. Of course, this makes her a big problem for the Dark Knight. Her constant run-ins with him make her one of the biggest Batman Rogues Gallery villains he has!