16. Increased Inflammation

Circadian rhythm disruption is associated with a rise in inflammatory markers and persistent low-grade inflammation throughout the body.
Studies reveal that people with misaligned sleep-wake cycles have higher levels of C-reactive protein and other inflammation indicators.
This chronic inflammation increases the risk for a variety of diseases, including cardiovascular and autoimmune disorders.
Synchronizing daily rhythms helps regulate the immune response and may reduce the harmful effects of inflammation, supporting long-term health.