When most people think of the search for aliens, vast star fields and distant planets come to mind. Yet, scientists are venturing far beyond these obvious realms, exploring some truly unexpected and unconventional locations in their quest for life beyond Earth. From the deepest ocean trenches to the mysterious clouds of other planets, researchers are employing creative and surprising strategies. These innovative approaches push the boundaries of what we consider possible habitats for extraterrestrial life, making the hunt for aliens more fascinating—and strange—than ever before.