6. Beta-Site APP-Cleaving Enzyme 1 (BACE1) Activity
Beta-site APP-cleaving enzyme 1 (BACE1) plays a central role in the production of amyloid beta, a key driver of Alzheimer’s pathology. Research indicates that BACE1 activity rises during the preclinical stages of the disease. By measuring BACE1 levels in the blood, clinicians may be able to identify Alzheimer’s before symptoms begin. For more details, refer to Translational Psychiatry.