19. Horse: Menopausal Relief Provider

Pregnant mare urine contains conjugated estrogens used in Premarin, approved in 1942 for menopausal symptom relief. The medication alleviates hot flashes, vaginal dryness, and bone density loss. Its production raises animal welfare concerns about urine collection methods. Synthetic estrogen alternatives exist, but many physicians still prescribe Premarin. The medication’s long safety record and effectiveness for severe symptoms maintain its place in hormone replacement therapy despite controversies.